Environmental Toxicology Diary

What is the mechanism of teratogenic action?
What are teratogenic agents?
The most dangerous effect of exposure to a toxic substance occurs when it impacts fetal development and the birth of a child. At birth, the number of children identified as having either a major or minor malformation is approximately 5 percent. Toxic agents that cause […]

UV is a physical agent that can cause mutation of our skin. UV from the sun is known to cause cancer as a result of prologed exposure. UV radiation affects the bonds between adjacent pyrimidines located on the same or opposite DNA strands. When this happens, thymine, for example, will bond to thymine forming […]

This post will briefly describe these questions:
What is excretion?
What are the organs for excretion?
What is excretion?
Excretion is the process of eliminating waste products of metabolism and other materials that are of no use. The rate at which excretion of toxic substances occurs is important in determining the toxicity of a substance. The faster a substance […]

What is phase II reactions?
What are types of phase II reactions?
What is phase II reactions?
During phase II reactions, the toxic substances or its metabolite is bound with a compound that generally renders the newly synthesized molecule less toxic. This type of reaction is referred to as conjugation. Conjugation is the joining of two substances […]

What is metabolism?
How does the toxicant biotransformed?
What are factors affecting metabolism?
What is metabolism?
Metabolism or often referred to biotransformation is a process which result in changing in the chemical structure of the toxic substance. These changes in a variety of tissue such as liver, kidney, lung, skin and GI tract as well. Primary spot for biotransformation […]